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A small library of chalcones induce liver cancer cell death through Akt phosphorylation inhibition

Hepatocellular carcinoma (HCC) ranks as the fifth most common and the second deadliest cancer worldwide. HCC is extremely resistant to the conventional chemotherapeutics. Hence, it is vital to develop new treatment options. Chalcones were previously shown to have anticancer activities in other cance...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sahin, Irem Durmaz, Christodoulou, Michael S., Guzelcan, Ece Akhan, Koyas, Altay, Karaca, Cigdem, Passarella, Daniele, Cetin-Atalay, Rengul
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367369/
https://ncbi.nlm.nih.gov/pubmed/32678233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68775-9
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