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A small library of chalcones induce liver cancer cell death through Akt phosphorylation inhibition

Hepatocellular carcinoma (HCC) ranks as the fifth most common and the second deadliest cancer worldwide. HCC is extremely resistant to the conventional chemotherapeutics. Hence, it is vital to develop new treatment options. Chalcones were previously shown to have anticancer activities in other cance...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Sahin, Irem Durmaz, Christodoulou, Michael S., Guzelcan, Ece Akhan, Koyas, Altay, Karaca, Cigdem, Passarella, Daniele, Cetin-Atalay, Rengul
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367369/
https://ncbi.nlm.nih.gov/pubmed/32678233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68775-9
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