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Synthesis and cellular bioactivities of novel isoxazole derivatives incorporating an arylpiperazine moiety as anticancer agents

In our endeavour towards the development of effective anticancer therapeutics, a novel series of isoxazole-piperazine hybrids were synthesized and evaluated for their cytotoxic activities against human liver (Huh7 and Mahlavu) and breast (MCF-7) cancer cell lines. Within series, compounds 5l-o showe...

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Bibliografiske detaljer
Udgivet i:J Enzyme Inhib Med Chem
Main Authors: Çalışkan, Burcu, Sinoplu, Esra, İbiş, Kübra, Akhan Güzelcan, Ece, Çetin Atalay, Rengül, Banoglu, Erden
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161610/
https://ncbi.nlm.nih.gov/pubmed/30251900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1504041
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