Nucleosome binding by the pioneer transcription factor OCT4

Transcription factor binding to genomic DNA is generally prevented by nucleosome formation, in which the DNA is tightly wrapped around the histone octamer. In contrast, pioneer transcription factors efficiently bind their target DNA sequences within the nucleosome. OCT4 has been identified as a pion...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Echigoya, Kenta, Koyama, Masako, Negishi, Lumi, Takizawa, Yoshimasa, Mizukami, Yuka, Shimabayashi, Hideki, Kuroda, Akari, Kurumizaka, Hitoshi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367260/
https://ncbi.nlm.nih.gov/pubmed/32678275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68850-1
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