TFII-I-mediated polymerase pausing antagonizes GLI2 induction by TGFβ

The modulation of GLI2, an oncogenic transcription factor commonly upregulated in cancer, is in many cases not due to genetic defects, suggesting dysregulation through alternative mechanisms. The identity of these molecular events remains for the most part unknown. Here, we identified TFII-I as a no...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: McCleary-Wheeler, Angela L, Paradise, Brooke D, Almada, Luciana L, Carlson, Annika J, Marks, David L, Vrabel, Anne, Vera, Renzo E, Sigafoos, Ashley N, Olson, Rachel L, Fernandez-Zapico, Martin E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Gene regulation, Chromatin and Epigenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367210/
https://ncbi.nlm.nih.gov/pubmed/32544250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa476
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi