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Cytosolic NUAK1 Enhances ATP Production by Maintaining Proper Glycolysis and Mitochondrial Function in Cancer Cells

NUAK1 is an AMPK-related kinase located in the cytosol and the nucleus, whose expression associates with tumor malignancy and poor patient prognosis in several cancers. Accordingly, NUAK1 was associated with metastasis because it promotes cell migration and invasion in different cancer cells. Beside...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Escalona, Emilia, Muñoz, Marcelo, Pincheira, Roxana, Elorza, Álvaro A., Castro, Ariel F.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367139/
https://ncbi.nlm.nih.gov/pubmed/32754444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01123
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