Oncolytic adenovirus ORCA‐010 increases the type 1 T cell stimulatory capacity of melanoma‐conditioned dendritic cells

Immune checkpoint blockade has resulted in durable responses in patients with metastatic melanoma, but only in a fraction of treated patients. For immune checkpoint inhibitors (ICI) to be effective, sufficient infiltration with tumor‐reactive T cells is essential. Oncolytic viruses (OV) selectively...

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Vydáno v:Clin Exp Immunol
Hlavní autoři: López González, M., van de Ven, R., de Haan, H., van Eck van der Sluijs, J., Dong, W., van Beusechem, V. W., de Gruijl, T. D.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366753/
https://ncbi.nlm.nih.gov/pubmed/32301504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13442
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