Sliced Human Cortical Organoids for Modeling Distinct Cortical Layer Formation

Human brain organoids provide unique platforms for modeling development and diseases by recapitulating the architecture of the embryonic brain. However, current organoid methods are limited by interior hypoxia and cell death due to insufficient surface diffusion, preventing generation of architectur...

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發表在:Cell Stem Cell
Main Authors: Qian, Xuyu, Su, Yijing, Adam, Christopher D., Deutschmann, Andre U., Pather, Sarshan R., Goldberg, Ethan M., Su, Kenong, Li, Shiying, Lu, Lu, Jacob, Fadi, Nguyen, Phuong T.T., Huh, Sooyoung, Hoke, Ahmet, Swinford-Jackson, Sarah E., Wen, Zhexing, Gu, Xiaosong, Pierce, R. Christopher, Wu, Hao, Briand, Lisa A., Chen, H. Isaac, Wolf, John A., Song, Hongjun, Ming, Guo-li
格式: Artigo
語言:Inglês
出版: 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366517/
https://ncbi.nlm.nih.gov/pubmed/32142682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.02.002
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