Sliced Human Cortical Organoids for Modeling Distinct Cortical Layer Formation

Human brain organoids provide unique platforms for modeling development and diseases by recapitulating the architecture of the embryonic brain. However, current organoid methods are limited by interior hypoxia and cell death due to insufficient surface diffusion, preventing generation of architectur...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Qian, Xuyu, Su, Yijing, Adam, Christopher D., Deutschmann, Andre U., Pather, Sarshan R., Goldberg, Ethan M., Su, Kenong, Li, Shiying, Lu, Lu, Jacob, Fadi, Nguyen, Phuong T.T., Huh, Sooyoung, Hoke, Ahmet, Swinford-Jackson, Sarah E., Wen, Zhexing, Gu, Xiaosong, Pierce, R. Christopher, Wu, Hao, Briand, Lisa A., Chen, H. Isaac, Wolf, John A., Song, Hongjun, Ming, Guo-li
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366517/
https://ncbi.nlm.nih.gov/pubmed/32142682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.02.002
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