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Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism

Neurological complications are common in patients with COVID-19. While SARS-CoV-2, the causal pathogen of COVID-19, has been detected in some patient brains, its ability to infect brain cells and impact their function are not well understood, and experimental models using human brain cells are urgen...

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Detalhes bibliográficos
Publicado no:bioRxiv
Principais autores: Jacob, Fadi, Pather, Sarshan R., Huang, Wei-Kai, Wong, Samuel Zheng Hao, Zhou, Haowen, Zhang, Feng, Cubitt, Beatrice, Chen, Catherine Z., Xu, Miao, Pradhan, Manisha, Zhang, Daniel Y., Zheng, Wei, Bang, Anne G., Song, Hongjun, de a Torre, Juan Carlos, Ming, Guo-li
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7402032/
https://ncbi.nlm.nih.gov/pubmed/32766575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.07.28.225151
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