Drug Inhibition of SARS-CoV-2 Replication in Human Pluripotent Stem Cell–Derived Intestinal Organoids

BACKGROUND AND AIMS: The COVID-19 pandemic has spread worldwide and poses a severe health risk. While most patients present mild symptoms, descending pneumonia can lead to severe respiratory insufficiency. Up to 50% of patients show gastrointestinal symptoms like diarrhea or nausea, intriguingly ass...

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Bibliografske podrobnosti
izdano v:Cell Mol Gastroenterol Hepatol
Main Authors: Krüger, Jana, Groß, Rüdiger, Conzelmann, Carina, Müller, Janis A., Koepke, Lennart, Sparrer, Konstantin M.J., Weil, Tatjana, Schütz, Desiree, Seufferlein, Thomas, Barth, Thomas F.E., Stenger, Steffen, Heller, Sandra, Münch, Jan, Kleger, Alexander
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655023/
https://ncbi.nlm.nih.gov/pubmed/33186749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.11.003
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