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IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro
Interferon-induced transmembrane proteins (IFITMs 1, 2 and 3) can restrict viral pathogens, but pro- and anti-viral activities have been reported for coronaviruses. Here, we show that artificial overexpression of IFITMs blocks SARS-CoV-2 infection. However, endogenous IFITM expression supports effic...
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| Vydáno v: | Nat Commun |
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| Hlavní autoři: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8319209/ https://ncbi.nlm.nih.gov/pubmed/34321474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24817-y |
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