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The Lac Repressor hinge helix in context: the effect of the DNA binding domain and symmetry

The Lac system of genes has been an important model system in understanding gene regulation. When the dimer lac repressor protein binds to the correct DNA sequence, the hinge region of the protein goes through a disorder to order transition. The hinge region is disordered when binding to nonoperator...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochim Biophys Acta Gen Subj
Prif Awduron: Seckfort, Danielle, Lynch, Gillian C., Pettitt, B. Montgomery
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366509/
https://ncbi.nlm.nih.gov/pubmed/31958546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2020.129538
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