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The Lac Repressor hinge helix in context: the effect of the DNA binding domain and symmetry

The Lac system of genes has been an important model system in understanding gene regulation. When the dimer lac repressor protein binds to the correct DNA sequence, the hinge region of the protein goes through a disorder to order transition. The hinge region is disordered when binding to nonoperator...

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Bibliografski detalji
Izdano u:Biochim Biophys Acta Gen Subj
Glavni autori: Seckfort, Danielle, Lynch, Gillian C., Pettitt, B. Montgomery
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366509/
https://ncbi.nlm.nih.gov/pubmed/31958546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2020.129538
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