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The Lac Repressor hinge helix in context: the effect of the DNA binding domain and symmetry

The Lac system of genes has been an important model system in understanding gene regulation. When the dimer lac repressor protein binds to the correct DNA sequence, the hinge region of the protein goes through a disorder to order transition. The hinge region is disordered when binding to nonoperator...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Gen Subj
Main Authors: Seckfort, Danielle, Lynch, Gillian C., Pettitt, B. Montgomery
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366509/
https://ncbi.nlm.nih.gov/pubmed/31958546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2020.129538
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