Hinge-helix formation and DNA bending in various lac repressor-operator complexes.

The hinge-region of the lac repressor plays an important role in the models for induction and DNA looping in the lac operon. When lac repressor is bound to a tight-binding symmetric operator, this region forms an alpha-helix that induces bending of the operator. The presence of the hinge-helices is...

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Bibliographic Details
Main Authors: Spronk, C A, Folkers, G E, Noordman, A M, Wechselberger, R, van den Brink, N, Boelens, R, Kaptein, R
Format: Artigo
Language:Inglês
Published: 1999
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171710/
https://ncbi.nlm.nih.gov/pubmed/10562559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.22.6472
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