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Hinge-helix formation and DNA bending in various lac repressor-operator complexes.
The hinge-region of the lac repressor plays an important role in the models for induction and DNA looping in the lac operon. When lac repressor is bound to a tight-binding symmetric operator, this region forms an alpha-helix that induces bending of the operator. The presence of the hinge-helices is...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1999
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171710/ https://ncbi.nlm.nih.gov/pubmed/10562559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.22.6472 |
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