Regulation of Mitochondrial Proliferation by PGC-1α Induces Cellular Apoptosis in Musculoskeletal Malignancies

A number of studies have reported that decreased mitochondrial numbers are linked with neoplastic transformation and/or tumor progression, including resistance to apoptosis. Peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α) is a multi-functional transcriptional coactivato...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Onishi, Yasuo, Ueha, Takeshi, Kawamoto, Teruya, Hara, Hitomi, Toda, Mitsunori, Harada, Risa, Minoda, Masaya, Kurosaka, Masahiro, Akisue, Toshihiro
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7365312/
https://ncbi.nlm.nih.gov/pubmed/24472748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03916
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