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Transcriptomic Analysis of Cellular Pathways in Healing Flexor Tendons of Plasminogen Activator Inhibitor 1 (PAI-1/Serpine1) Null Mice

Injuries to flexor tendons can be complicated by fibrotic adhesions, which severely impair the function of the hand. Plasminogen Activator Inhibitor 1 (PAI-1/SERPINE1), a master suppressor of fibrinolysis and protease activity, is associated with adhesions. Here, we used next-generation RNA sequenci...

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Detalhes bibliográficos
Publicado no:J Orthop Res
Main Authors: Freeberg, Margaret A. T., Easa, Anas, Lillis, Jacquelyn A., Benoit, Danielle S.W., van Wijnen, Andre J., Awad, Hani A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7364818/
https://ncbi.nlm.nih.gov/pubmed/31424116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.24448
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