Enhanced Susceptibility to Chemoconvulsant-Induced Seizures in Ganglioside GM3 Synthase Knockout Mice

Ganglioside GM3 synthase (α-2,3-sialyltransferase, ST3GAL5, GM3S) is a key enzyme involved in the biosynthesis of gangliosides. ST3GAL5 deficiency causes an absence of GM3 and all downstream biosynthetic derivatives. The affected individuals manifest deafness, severe irritability, intractable seizur...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:ASN Neuro
Egile Nagusiak: Tang, Fu-Lei, Wang, Jing, Itokazu, Yukata, Yu, Robert K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: SAGE Publications 2020
Gaiak:
Original Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7364800/
https://ncbi.nlm.nih.gov/pubmed/32664815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1759091420938175
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