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A reduced susceptibility to chemoconvulsant stimulation in adenylyl cyclase 8 knockout mice
OBJECTIVE: Adenylyl cyclases (ACs) catalyze the synthesis of cAMP from ATP, and cAMP signaling affects a large number of neuronal processes. Ca(2+)-stimualted adenylyl cyclase 8 (AC8) expressed in the CNS plays a role in synaptic plasticity, drug addiction and ethanol sensitivity, and chronic pain....
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| Publicado no: | Epilepsy Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4698032/ https://ncbi.nlm.nih.gov/pubmed/26656781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eplepsyres.2015.11.007 |
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