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Absence of polo-like kinase 3 in mice stabilizes Cdc25A after DNA damage but is not sufficient to produce tumors

The polo-like kinases (Plks1–5) are emerging as an important class of proteins involved in many facets of cell cycle regulation and response to DNA damage and stress. Here we show that Plk3 phosphorylates the key cell cycle protein phosphatase Cdc25A on two serine residues in its cyclinB/cdk1 dockin...

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Detalhes bibliográficos
Publicado no:Mutat Res
Main Authors: Myer, David L., Robbins, Susan B., Yin, Moying, Boivin, Gregory P., Liu, Yang, Greis, Kenneth D., Bahassi, El Mustapha, Stambrook, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7364384/
https://ncbi.nlm.nih.gov/pubmed/21376736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2011.02.006
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