Stem Cell-Derived Viral Antigen-Specific T Cells Suppress HBV Replication through Production of IFN-γ and TNF-⍺

The viral antigen (Ag)-specific CD8(+) cytotoxic T lymphocytes (CTLs) derived from pluripotent stem cells (PSCs), i.e., PSC-CTLs, have the ability to suppress hepatitis B virus (HBV) infection. After adoptive transfer, PSC-CTLs can infiltrate into the liver to suppress HBV replication. Nevertheless,...

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Pubblicato in:iScience
Autori principali: Haque, Mohammad, Lei, Fengyang, Xiong, Xiaofang, Ren, Yijie, Kumar, Anil, Das, Jugal Kishore, Ren, Xingcong, Fang, Deyu, de Figueiredo, Paul, Yang, Jin-Ming, Song, Jianxun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7364173/
https://ncbi.nlm.nih.gov/pubmed/32679546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101333
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