Stem Cell-Derived Viral Antigen-Specific T Cells Suppress HIV Replication and PD-1 Expression on CD4+ T Cells

The viral antigen (Ag)-specific CD8+ cytotoxic T lymphocytes (CTLs) derived from pluripotent stem cells (PSCs), i.e., PSC-CTLs, have the ability to suppress the human immunodeficiency virus (HIV) infection. After adoptive transfer, PSC-CTLs can infiltrate into the local tissues to suppress HIV repli...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Haque, Mohammad, Lei, Fengyang, Xiong, Xiaofang, Ren, Yijie, Peng, Hao-Yun, Wang, Liqing, Kumar, Anil, Das, Jugal Kishore, Song, Jianxun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8146941/
https://ncbi.nlm.nih.gov/pubmed/33923025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13050753
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