Mitochondrial dysfunction impairs osteogenesis, increases osteoclast activity, and accelerates age related bone loss

The pathogenesis of declining bone mineral density, a universal feature of ageing, is not fully understood. Somatic mitochondrial DNA (mtDNA) mutations accumulate with age in human tissues and mounting evidence suggests that they may be integral to the ageing process. To explore the potential effect...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Dobson, Philip F., Dennis, Ella P., Hipps, Daniel, Reeve, Amy, Laude, Alex, Bradshaw, Carla, Stamp, Craig, Smith, Anna, Deehan, David J., Turnbull, Doug M., Greaves, Laura C.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363892/
https://ncbi.nlm.nih.gov/pubmed/32669663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68566-2
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki