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Highly synergistic antimicrobial activity of magainin 2 and PGLa peptides is rooted in the formation of supramolecular complexes with lipids

Magainin 2 and PGLa are cationic, amphipathic antimicrobial peptides which when added as equimolar mixture exhibit a pronounced synergism in both their antibacterial and pore-forming activities. Here we show for the first time that the peptides assemble into defined supramolecular structures along t...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Aisenbrey, Christopher, Amaro, Mariana, Pospíšil, Petr, Hof, Martin, Bechinger, Burkhard
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363891/
https://ncbi.nlm.nih.gov/pubmed/32669585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68416-1
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