Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ

The transcription factor Sox21 is expressed in the epithelium of developing teeth. The present study aimed to determine the role of Sox21 in tooth development. We found that disruption of Sox21 caused severe enamel hypoplasia, regional osteoporosis, and ectopic hair formation in the gingiva in Sox21...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Saito, Kan, Michon, Frederic, Yamada, Aya, Inuzuka, Hiroyuki, Yamaguchi, Satoko, Fukumoto, Emiko, Yoshizaki, Keigo, Nakamura, Takashi, Arakaki, Makiko, Chiba, Yuta, Ishikawa, Masaki, Okano, Hideyuki, Thesleff, Irma, Fukumoto, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363706/
https://ncbi.nlm.nih.gov/pubmed/32674056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101329
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