Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ

The transcription factor Sox21 is expressed in the epithelium of developing teeth. The present study aimed to determine the role of Sox21 in tooth development. We found that disruption of Sox21 caused severe enamel hypoplasia, regional osteoporosis, and ectopic hair formation in the gingiva in Sox21...

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Publicat a:iScience
Autors principals: Saito, Kan, Michon, Frederic, Yamada, Aya, Inuzuka, Hiroyuki, Yamaguchi, Satoko, Fukumoto, Emiko, Yoshizaki, Keigo, Nakamura, Takashi, Arakaki, Makiko, Chiba, Yuta, Ishikawa, Masaki, Okano, Hideyuki, Thesleff, Irma, Fukumoto, Satoshi
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363706/
https://ncbi.nlm.nih.gov/pubmed/32674056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101329
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