Targeting Macrophages by an Aza-Anthrapyrazole to Ameliorate Experimental Autoimmune Encephalomyelitis

BACKGROUND: Multiple sclerosis (MS) is an immune-mediated neurodegenerative disease in the central nerve system, in which both innate and adaptive immune cells are involved. BBR3378, an aza-anthrapyrazole prevents experimental autoimmune encephalomyelitis (EAE), an inflammatory condition similar to...

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Veröffentlicht in:Mult Scler Relat Disord
Hauptverfasser: Lin, Boren, Launder, Dylan, Bailey, Destiny Y., Assifuah, Frank K., Miller, Olivia A., Conti, Heather R., Du, Jianyang, Koffman, Boyd M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363561/
https://ncbi.nlm.nih.gov/pubmed/32447250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.msard.2020.102190
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