Clonal diversity revealed by morphoproteomic and copy number profiles of single prostate cancer cells at diagnosis

Tumor heterogeneity is prevalent in both treatment-naïve and end-stage metastatic castration-resistant prostate cancer (PCa), and may contribute to the broad range of clinical presentation, treatment response, and disease progression. To characterize molecular heterogeneity associated with de novo m...

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Pubblicato in:Converg Sci Phys Oncol
Autori principali: Malihi, Paymaneh D, Morikado, Michael, Welter, Lisa, Liu, Sandy T, Miller, Eric T, Cadaneanu, Radu M, Knudsen, Beatrice S, Lewis, Michael S, Carlsson, Anders, Velasco, Carmen Ruiz, Kolatkar, Anand, Rodriguez-Lee, Mariam, Garraway, Isla P, Hicks, James, Kuhn, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363158/
https://ncbi.nlm.nih.gov/pubmed/32670616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/2057-1739/aaa00b
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