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In vitro assays for effector T cell functions and activity of immunomodulatory antibodies

The recent clinical success of cancer immunotherapy with checkpoint blockade has led to renewed interest into the development of immune modulatory agents with the capacity to activate anti-tumor T cell responses. Standardization of optimized in vitro assays for efficient assessment of immune functio...

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Detalhes bibliográficos
Publicado no:Methods Enzymol
Main Authors: Zappasodi, Roberta, Budhu, Sadna, Abu-Akeel, Mohsen, Merghoub, Taha
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7362725/
https://ncbi.nlm.nih.gov/pubmed/31948562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.08.012
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