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Curvature and Torsion of Protein Main Chain as Local Order Parameters of Protein Unfolding

Thermal protein unfolding resembles a global (two-state) phase transition. At the local scale, protein unfolding is, however, heterogeneous and probe dependent. Here, we consider local order parameters defined by the local curvature and torsion of the protein main chain. Because chemical shifts (CS)...

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Bibliografiska uppgifter
I publikationen:J Phys Chem B
Huvudupphovsmän: Grassein, Paul, Delarue, Patrice, Nicolaï, Adrien, Neiers, Fabrice, Scheraga, Harold A., Maisuradze, Gia G., Senet, Patrick
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7362589/
https://ncbi.nlm.nih.gov/pubmed/32392067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.0c01230
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