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How main-chains of proteins explore the free-energy landscape in native states

Understanding how a single native protein diffuses on its free-energy landscape is essential to understand protein kinetics and function. The dynamics of a protein is complex, with multiple relaxation times reflecting a hierarchical free-energy landscape. Using all-atom molecular dynamics simulation...

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Detalhes bibliográficos
Main Authors: Senet, Patrick, Maisuradze, Gia G., Foulie, Colette, Delarue, Patrice, Scheraga, Harold A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604949/
https://ncbi.nlm.nih.gov/pubmed/19073932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810679105
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