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How Adequate are One- and Two-Dimensional Free Energy Landscapes for Protein Folding Dynamics?

The molecular dynamics trajectories of protein folding or unfolding, generated with the coarse-grained united-residue force field for the B domain of staphylococcal protein A, were analyzed by principal component analysis (PCA). The folding or unfolding process was examined by using free-energy land...

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Bibliografiske detaljer
Main Authors: Maisuradze, Gia G., Liwo, Adam, Scheraga, Harold A.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760970/
https://ncbi.nlm.nih.gov/pubmed/19658975
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