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How main-chains of proteins explore the free-energy landscape in native states
Understanding how a single native protein diffuses on its free-energy landscape is essential to understand protein kinetics and function. The dynamics of a protein is complex, with multiple relaxation times reflecting a hierarchical free-energy landscape. Using all-atom molecular dynamics simulation...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2604949/ https://ncbi.nlm.nih.gov/pubmed/19073932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810679105 |
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