H3K27ac acetylome signatures reveal the epigenomic reorganization in remodeled non-failing human hearts

BACKGROUND: H3K27ac histone acetylome changes contribute to the phenotypic response in heart diseases, particularly in end-stage heart failure. However, such epigenetic alterations have not been systematically investigated in remodeled non-failing human hearts. Therefore, valuable insight into cardi...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Pei, Jiayi, Harakalova, Magdalena, Treibel, Thomas A., Lumbers, R Thomas, Boukens, Bastiaan J., Efimov, Igor R., van Dinter, Jip T., González, Arantxa, López, Begoña, El Azzouzi, Hamid, van den Dungen, Noortje, van Dijk, Christian G. M., Krebber, Merle M., den Ruijter, Hester M., Pasterkamp, Gerard, Duncker, Dirk J., Nieuwenhuis, Edward E. S., de Weger, Roel, Huibers, Manon M., Vink, Aryan, Moore, Jason H., Moon, James C., Verhaar, Marianne C., Kararigas, Georgios, Mokry, Michal, Asselbergs, Folkert W., Cheng, Caroline
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7362435/
https://ncbi.nlm.nih.gov/pubmed/32664951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00895-5
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