Chromatin Conformation Links Distal Target Genes to CKD Loci

Genome-wide association studies (GWASs) have identified many genetic risk factors for CKD. However, linking common variants to genes that are causal for CKD etiology remains challenging. By adapting self-transcribing active regulatory region sequencing, we evaluated the effect of genetic variation o...

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Detalles Bibliográficos
Publicado en:J Am Soc Nephrol
Autores principales: Brandt, Maarten M., Meddens, Claartje A., Louzao-Martinez, Laura, van den Dungen, Noortje A.M., Lansu, Nico R., Nieuwenhuis, Edward E.S., Duncker, Dirk J., Verhaar, Marianne C., Joles, Jaap A., Mokry, Michal, Cheng, Caroline
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2018
Materias:
Basic Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791087/
https://ncbi.nlm.nih.gov/pubmed/29093029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016080875
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