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Systematic analysis of chromatin interactions at disease associated loci links novel candidate genes to inflammatory bowel disease

BACKGROUND: Genome-wide association studies (GWAS) have revealed many susceptibility loci for complex genetic diseases. For most loci, the causal genes have not been identified. Currently, the identification of candidate genes is predominantly based on genes that localize close to or within identifi...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Meddens, Claartje A., Harakalova, Magdalena, van den Dungen, Noortje A. M., Foroughi Asl, Hassan, Hijma, Hemme J., Cuppen, Edwin P. J. G., Björkegren, Johan L. M., Asselbergs, Folkert W., Nieuwenhuis, Edward E. S., Mokry, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131449/
https://ncbi.nlm.nih.gov/pubmed/27903283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1100-3
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