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Tackling COVID‐19 infection through complement‐targeted immunotherapy

The complement system is an ancient part of innate immunity sensing highly pathogenic coronaviruses by mannan‐binding lectin (MBL) resulting in lectin pathway activation and subsequent generation of the anaphylatoxins (ATs) C3a and C5a as important effector molecules. Complement deposition on endoth...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Jodele, Sonata, Köhl, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7361469/
https://ncbi.nlm.nih.gov/pubmed/32643798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15187
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