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Targeting complement activation in COVID-19
In this issue of Blood, Yu et al have demonstrated that acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike proteins activate complement by engaging the alternative pathway (AP) and that blocking this process by inhibiting factor D or C5 could mitigate SARS-CoV-2–induced immunopathology.(1)...
Tallennettuna:
| Julkaisussa: | Blood |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society of Hematology
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7596848/ https://ncbi.nlm.nih.gov/pubmed/33119763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020008925 |
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