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Targeting complement activation in COVID-19
In this issue of Blood, Yu et al have demonstrated that acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike proteins activate complement by engaging the alternative pathway (AP) and that blocking this process by inhibiting factor D or C5 could mitigate SARS-CoV-2–induced immunopathology.(1)...
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| Publié dans: | Blood |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Hematology
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7596848/ https://ncbi.nlm.nih.gov/pubmed/33119763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020008925 |
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