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Tackling COVID‐19 infection through complement‐targeted immunotherapy

The complement system is an ancient part of innate immunity sensing highly pathogenic coronaviruses by mannan‐binding lectin (MBL) resulting in lectin pathway activation and subsequent generation of the anaphylatoxins (ATs) C3a and C5a as important effector molecules. Complement deposition on endoth...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Jodele, Sonata, Köhl, Jörg
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7361469/
https://ncbi.nlm.nih.gov/pubmed/32643798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15187
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