New Multidrug Efflux Inhibitors for Gram-Negative Bacteria

Active efflux of antibiotics preventing their accumulation to toxic intracellular concentrations contributes to clinically relevant multidrug resistance. Inhibition of active efflux potentiates antibiotic activity, indicating that efflux inhibitors could be used in combination with antibiotics to re...

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Bibliographic Details
Published in:mBio
Main Authors: Marshall, Robert L., Lloyd, Georgina S., Lawler, Amelia J., Element, Sarah J., Kaur, Jaswant, Ciusa, Maria Laura, Ricci, Vito, Tschumi, Andreas, Kühne, Holger, Alderwick, Luke J., Piddock, Laura J. V.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2020
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7360932/
https://ncbi.nlm.nih.gov/pubmed/32665275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01340-20
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