New Multidrug Efflux Inhibitors for Gram-Negative Bacteria

Active efflux of antibiotics preventing their accumulation to toxic intracellular concentrations contributes to clinically relevant multidrug resistance. Inhibition of active efflux potentiates antibiotic activity, indicating that efflux inhibitors could be used in combination with antibiotics to re...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Marshall, Robert L., Lloyd, Georgina S., Lawler, Amelia J., Element, Sarah J., Kaur, Jaswant, Ciusa, Maria Laura, Ricci, Vito, Tschumi, Andreas, Kühne, Holger, Alderwick, Luke J., Piddock, Laura J. V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7360932/
https://ncbi.nlm.nih.gov/pubmed/32665275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01340-20
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