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ATM-associated signalling triggers the unfolded protein response and cell death in response to stress
Endoplasmic reticulum (ER) stress can be caused by perturbations in ER function resulting from the accumulation of unfolded/misfolded proteins in the ER lumen. Accumulating unfolded proteins trigger unfolded protein responses (UPRs) through activating three transmembrane sensors on the ER: IRE1α, PE...
Enregistré dans:
| Publié dans: | Commun Biol |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7360780/ https://ncbi.nlm.nih.gov/pubmed/32665601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-1102-2 |
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