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ATM-associated signalling triggers the unfolded protein response and cell death in response to stress
Endoplasmic reticulum (ER) stress can be caused by perturbations in ER function resulting from the accumulation of unfolded/misfolded proteins in the ER lumen. Accumulating unfolded proteins trigger unfolded protein responses (UPRs) through activating three transmembrane sensors on the ER: IRE1α, PE...
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| Publicat a: | Commun Biol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7360780/ https://ncbi.nlm.nih.gov/pubmed/32665601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-1102-2 |
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