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ATM-associated signalling triggers the unfolded protein response and cell death in response to stress
Endoplasmic reticulum (ER) stress can be caused by perturbations in ER function resulting from the accumulation of unfolded/misfolded proteins in the ER lumen. Accumulating unfolded proteins trigger unfolded protein responses (UPRs) through activating three transmembrane sensors on the ER: IRE1α, PE...
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| Publicado no: | Commun Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7360780/ https://ncbi.nlm.nih.gov/pubmed/32665601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-1102-2 |
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