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Loss of α(2)δ-1 Calcium Channel Subunit Function Increases the Susceptibility for Diabetes
Reduced pancreatic β-cell function or mass is the critical problem in developing diabetes. Insulin release from β-cells depends on Ca(2+) influx through high voltage– gated Ca(2+) channels (HVCCs). Ca(2+) influx also regulates insulin synthesis and insulin granule priming and contributes to β-cell e...
Gorde:
| Argitaratua izan da: | Diabetes |
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| Egile Nagusiak: | , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2017
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7360433/ https://ncbi.nlm.nih.gov/pubmed/28115397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0336 |
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