N6-methyladenosine Modulates Nonsense-mediated mRNA Decay in Human Glioblastoma

The N6-methyladenosine (m(6)A) modification influences various mRNA metabolic events and tumorigenesis, however, its functions in nonsense-mediated mRNA decay (NMD) and whether NMD detects induced carcinogenesis pathways remain undefined. Here, we showed that the m(6)A methyltransferase METTL3 susta...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Li, Fuxi, Yi, Yang, Miao, Yanyan, Long, Wenyong, Long, Teng, Chen, Siyun, Cheng, Weisheng, Zou, Changye, Zheng, Yueyuan, Wu, Xingui, Ding, Junjun, Zhu, Kaiyu, Chen, Delin, Xu, Qiongcong, Wang, Jinkai, Liu, Qing, Zhi, Feng, Ren, Jian, Cao, Qi, Zhao, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7360104/
https://ncbi.nlm.nih.gov/pubmed/31530567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-2868
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