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Deep learning approach for quantification of organelles and misfolded polypeptide delivery within degradative compartments

Endolysosomal compartments maintain cellular fitness by clearing dysfunctional organelles and proteins from cells. Modulation of their activity offers therapeutic opportunities. Quantification of cargo delivery to and/or accumulation within endolysosomes is instrumental for characterizing lysosome-d...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Morone, Diego, Marazza, Alessandro, Bergmann, Timothy J., Molinari, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359569/
https://ncbi.nlm.nih.gov/pubmed/32401604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-04-0269
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