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Deep learning approach for quantification of organelles and misfolded polypeptide delivery within degradative compartments

Endolysosomal compartments maintain cellular fitness by clearing dysfunctional organelles and proteins from cells. Modulation of their activity offers therapeutic opportunities. Quantification of cargo delivery to and/or accumulation within endolysosomes is instrumental for characterizing lysosome-d...

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Bibliografische gegevens
Gepubliceerd in:Mol Biol Cell
Hoofdauteurs: Morone, Diego, Marazza, Alessandro, Bergmann, Timothy J., Molinari, Maurizio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Cell Biology 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359569/
https://ncbi.nlm.nih.gov/pubmed/32401604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-04-0269
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