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Endogenous retrovirus activation as a key mechanism of anti-tumor immune response in radiotherapy

Generation of DNA double strand breaks has historically been taught as the mechanism through which radiotherapy (RT) kills cancer cells. Recently, it was recognized that radiation-induced cytosolic DNA release and activation of the cGAS/STING pathway, with ensuing induction of interferon secretion a...

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Detalhes bibliográficos
Publicado no:Radiat Res
Main Authors: Lee, Andrew K, Pan, Dong, Bao, Xuhui, Hu, Mengjie, Li, Fang, Li, Chuan-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359417/
https://ncbi.nlm.nih.gov/pubmed/32074012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RADE-20-00013
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