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Endogenous retrovirus activation as a key mechanism of anti-tumor immune response in radiotherapy

Generation of DNA double strand breaks has historically been taught as the mechanism through which radiotherapy (RT) kills cancer cells. Recently, it was recognized that radiation-induced cytosolic DNA release and activation of the cGAS/STING pathway, with ensuing induction of interferon secretion a...

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Pubblicato in:Radiat Res
Autori principali: Lee, Andrew K, Pan, Dong, Bao, Xuhui, Hu, Mengjie, Li, Fang, Li, Chuan-Yuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359417/
https://ncbi.nlm.nih.gov/pubmed/32074012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RADE-20-00013
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